Tiamos

 

Composition:

Each gram contains: ……………………………..450 mg tiamulin hydrogen fumarate

(Equ. to 364.2 mg tiamulin base)

Properties:

-Tiamulin is a semi-synthetic derivative of the antibiotic pleuromutilin. Tiamulin has bacteriostatic action, based on binding to bacterial ribosomes, thus inhibiting the action of the enzyme peptidyltransferase, finally resulting in the inhibition of protein synthesis. Tiamulin is mainly active in vitro against most Gram-positive bacteria, some Gram-negative bacteria, pathogenic Mycoplasma spp., Treponema spp. and Leptospira spp.Clostridium spp., Fusobacterium spp., Klebsiella spp., Mycoplasma spp. (M. arthritidis, M. gallisepticum, M. hyopneumoniae, M. hyorhinis, M. hyosynoviae, M. meleagridis, M. pulmonis, M. synoviae, etc.),Streptococci, Staphylococci Resistance develops very slowly
partial cross-resistance with erythromycin and tylosin is possible. After oral administration, tiamulin is quickly absorbed and maximal blood levels are obtained after about 2 hours.

 

Target Species

Pigs chicken

Indications

Chicken
Prevention and therapy of chronic respiratory diseases (CRD) and air sacculitis caused by M. gallisepticum and M. synoviae.
Turkeys
Prevention and therapy of infections sinusitis and air sacculitis caused by M. gallisepticum, M. synoviae and M. meleagridis.

 

CONTRA-INDICATIONS:

Do not use in breeding pigs or layers producing eggs for human consumption.

 

Dosage of Administration

Poultry: 0.5-1mg /kg bwt for 3-5 consecutive days

Route: Orally via drinking water

1-swine dysentery: 1 gm of product / 51 kg. b. wt. in drinking water/day for 5 consecutive days.

2-Enzootic pneumonia: 1.7-2.25  gm of product / 51  kg. b. wt  in drinking water/day for 5 consecutive days.

Warning & precaution:

-Avoid interactions between tiamulin and the ionophore products monensin, narasin and salinomycin.

Withdrawal times:

– Meat and offal : 5 days

Storage conditions

Store at temperature not exceeding 30 C° in dry place and use immediately after opening and use for 24 hours after reconstitution to be stored at temperature not exceeding 30 C ° away from light.

Package

50, 100, 250, 500, and 1000 ml.